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  • Apr
    11

    Amantadine- Parkinsons and Beyond

    Filed under: Parkinson; Tagged as: , ,

    Though Amantadine is prescribed for the treatment of influenza-A and symptoms of Parkinson’s disease, it has been found useful in treating other complications as well. Amantadine (a generic drug, also available under brand name Symmetrel) has surpassed the expectations of medical fraternity.

    Developed as a prescribed drug for the treatment of influenza-A in adults, Amantadine is also proving its weight in gold in treating other disorders as well. Amantadine is an anti-viral drug that can inhibit the replication of viruses in cells. It was approved by the FDA in 1966. The symptoms of Parkinson’s disease have long been treated by Amantadine. Of late, it has also been found useful in treating disorders like –

    Bed-wetting (in children)
    Some types of seizures
    Dementia
    Depression
    Drug-induced tremors, also known as Parkinsonism
    Traumatic head injury
    Some viral diseases (other than influenza)
    Problems due to brain injuries
    Multiple Sclerosis (MS)
    Fatigue related to MS
    Cocaine withdrawal

    According to unconfirmed reports, recently, amantadine was also used in China poultry farming in an effort to protect the birds against avian flu. The FDA has approved amantadine only for use in humans. Chickens in China have received an estimated 2.6 billion doses of amantadine. Avian flu strains in China and southeast Asia are resistant to amantadine, but strains circulating elsewhere seem to be sensitive. Amantadine might appear to be a wonder drug but is still not without its side effects.

    Common adverse reactions include – dizziness, constipation, a purple or blue network pattern on the skin, difficulty urinating, insomnia, nervousness, nausea, vomiting, headache, irritability, upset stomach (should be taken with food or milk), blurred vision, swelling of the ankles and depression. If you are pregnant, or plan to become pregnant, or breastfeeding, discuss the potential risks of this or any medication with your doctor. Use caution if over 60 years of age. The dosage should be adjusted accordingly.

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